Cytotoxic isoquinoline quinones from sponges of the genus Petrosia. Author
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Cytotoxic isoquinoline quinones from sponges of the genus Petrosia.
Bioassay-guided fractionation of two Philippine sponges of the genus Petrosia has resulted in the isolation of the novel natural product cribrostatin 7 (1) and the known compounds renierone (2) and O-demethylrenierone (3). The structures of these isoquinoline quinones were determined by interpretation of spectroscopic data. Compounds 1, 2 and 3 were cytotoxic against the HCT 116 human colon car...
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